FOR PARTNERS AND INVESTORS
An early-stage opportunity in a market that has been waiting for this.
Zera Medical is developing ZeraFlow, a clinic-based bowel preparation system that addresses a universally recognized, quantitatively large, and structurally unsolved problem in colorectal cancer screening. We are currently raising our initial SAFE round and selecting strategic partners for our U.S. launch.
THE OPPORTUNITY
Why ZeraFlow. Why now.
MARKET
$2.3B+
Pre-procedure U.S. colonoscopy ecosystem
15 million annual U.S. colonoscopies. No active clinic-based prep competitor in the United States. A category waiting to be defined.
PRODUCT
500+
International clinical procedures validated
97% prep adequacy rate. Peer-reviewed publication. FDA Class II 510(k) pathway in progress. 0 serious adverse events reported.¹
BUSINESS MODEL
67–80%
Estimated gross margin on consumables
High-margin, recurring per-procedure disposable revenue. Capital-efficient. Scales with procedure volume rather than fixed infrastructure.
STAGE
$1.2M
SAFE round currently in progress
Pre-seed. Series A anticipated following FDA clearance and U.S. pilot completion. Ground floor entry with clinical validation already behind it.
CLINICAL VALIDATION
500+
International procedures completed
96.3%
Prep adequacy rate (BBPS)²
98.4%
Patient
completion rate³
Zero
Serious adverse events reported⁴
MILESTONE ROADMAP
2013
Peer-reviewed publication
Ziv Y, Scapa E. Techniques in Coloproctology. Foundational clinical study published.
COMPLETE
2022–2025
500+ international clinical procedures completed
ZeraFlow validated across more than 500 procedures in Israel with no serious adverse events.
COMPLETE
2024
Zera Medical LLC founded
U.S. entity established to commercialize ZeraFlow for the North American market.
COMPLETE
2026
ZeraMed.com launches
Company website live. SAFE round in progress. Pilot site recruitment underway.
COMPLETE
2026
FDA 510(k) submission and clearance
Class II 510(k) submission in progress. Clearance anticipated Q2–Q3 2026.
IN PROGRESS
POST CLEARANCE
U.S. clinical pilot launch
Flagship pilot with 1–3 leading GI practices or ASCs. Target: approximately 1,000 procedures.
UPCOMING
2027
U.S. outcomes publication and regional expansion
U.S. pilot data prepared for peer-reviewed publication. Expansion to 5+ centers.
UPCOMING
GET IN TOUCH
Interested in learning more?
¹ ²³⁴ Ziv Y, Scapa E. Techniques in Coloproctology. 2013;17:39–44. DOI: 10.1007/s10151-012-0876-8.