ABOUT ZERA MEDICAL

Colorectal cancer is one of the most preventable cancers in the world. The prep is why millions of people are not screened.

Zera Medical was founded to fix that.

OUR MISSION

To remove the single greatest barrier to colorectal cancer screening by replacing the most dreaded part of colonoscopy with a predictable, dignified, clinical-grade preparation experience that works every time.

THE STORY

Why we built ZeraFlow

15M+

18–35%

compromised by inadequate bowel prep

40%+

colonoscopies performed annually in the U.S.

of eligible adults delay or avoid screening because of prep

More than 15 million colonoscopies are performed in the United States every year. Colonoscopy is the gold standard for colorectal cancer prevention. Yet millions of eligible adults delay or skip screening entirely, and the reason is not fear of the procedure. It is the preparation.

For decades, patients have been sent home with large volumes of harsh laxatives, given instructions that are difficult to follow, and left alone to manage an uncomfortable and unpredictable process. In 18 to 35% of cases, that process fails, leading to missed lesions, aborted procedures, and costly repeat visits.

Zera Medical was built on a simple belief: bowel preparation should not be the patient's problem. It should be the care team's responsibility. ZeraFlow moves prep into the clinic, under supervision, with consistent and predictable results. A better experience for the patient. A better procedure for the physician. A better outcome for everyone.

WHY NOW

Several forces are converging at once

Rising incidence in younger adults

Colorectal cancer rates are rising in adults aged 45 to 55, the fastest-growing screening cohort. Screening guidelines now include adults aged 45 and older, adding millions of newly eligible patients who have never experienced prep before.

GLP-1 medications complicating oral prep

The rapid adoption of GLP-1 medications significantly worsens traditional oral prep tolerance by slowing gastric emptying. A growing segment of the screening population now has a medical reason to avoid standard laxative regimens.

Provider pressure to improve efficiency

GI practices and ASCs face financial and reputational pressure from inadequate preps, repeat procedures, and day-of cancellations. ZeraFlow converts a chronic operational liability into a controllable, revenue-generating clinical step.

Consumer demand for dignified care

Patients increasingly expect preventive care to be convenient, comfortable, and modern. The generation now entering peak screening age has seen what better healthcare experiences look like and will seek them out.